Because the bacterias that create the diseases pertussis, tetanus, and diphtheria all cause harmful proteins called toxins they are able to be combined into one vaccine and addressing three infectious diseases in one.
The vaccine components include diphtheria and tetanus toxoids and either killed whole cells of the bacterium that causes pertussis or pertussis antigens. DTaP and Tdap are both combination vaccines. The lower-case "d" and "p" indicate smaller concentrations of diphtheria toxoids and pertussis antigens, and "a" in "ap/aP" indicates that the pertussis toxoids are acellular.
The DTaP and Tdap vaccines both protect against three bacterial infections: diphtheria, tetanus and pertussis, whereas the Td vaccine only protects against diphtheria and tetanus. In addition, the vaccines vary in terms of who should receive them and the quantities of vaccine proteins they contain:
𝙳𝚃𝚊𝙿: The DTaP vaccine is given to infants and young children in a series of five shots ─ at 2 months, 4 months, 6 months, 15 to 18 months, and again at 4 to 6 years of age.
𝚃𝚍𝚊𝚙: The Tdap vaccine is different from the DTaP vaccine because it contains lesser quantities of diphtheria and pertussis proteins. For this reason, Tdap is much less likely than DTaP to cause side effects such as pain, redness and tenderness in adolescents and adults. The Tdap vaccine is recommended for most people 11 years and older who have not previously received it. People due for a tetanus booster and those with a wound that warrants tetanus vaccination can get Tdap or Td vaccine.
𝚃𝚍: The Td vaccine is the one people commonly think of when they think of getting their tetanus booster. Like Tdap, it contains lesser quantities of diphtheria protein to reduce the occurrence of side effects in adults. Adults should get a dose of Tdap or Td every 10 years as well as if they have a wound that warrants tetanus vaccination.
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